Knowledge Base

Stratum corneum

The stratum corneum is the outermost layer of the epidermis and consists of a series of layers of dead cells (corneocytes) which are continuously shedding. Additionally, the stratum corneum aids in hydration and water retention, which prevents cracking. It is made up of corneocytes, which are anucleated keratinocytes that have reached the final stage of keratinocyte differentiation.