Knowledge Base

Interleukin-1

There are two forms of interleukin-1 (IL-1), IL-1α and IL-1β Both forms are produced by macrophages, monocytes and dendritic cells – cells involved in the innate immune response.

Interleukin-1 is an important part of body's inflammatory response against infection. It enables transmigration of leukocytes (the cells that fight pathogens), helps to increase body temperature (helping the immune system to fight infection) and regulates hematopoiesis (the formation of blood cells).