Knowledge Base

Inflammatory cytokine

Inflammatory cytokine is a signaling molecule, which is excreted from immune cells (and certain other cells) and contributes to the enhancement of inflammation process. They include interleukin-1 (IL-1), IL-12, and IL-18, tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ), etc. Excessive chronic production of inflammatory cytokines contribute to inflammatory diseases, that have been linked to different diseases, such as atherosclerosis and cancer. A balance between proinflammatory and anti-inflammatory cytokines is necessary to maintain health.