Knowledge Base

Acid-base homeostasis

Acid-base homeostasis and pH regulation are critical for both normal physiology and cell metabolism and function. Normally, systemic acid-base balance is well regulated, with arterial pH between 7.36 and 7.44; intracellular pH is usually approximately 7.2.

Extracellular fluid (ECF) refers to all bodily fluid outside the cells of any multicellular organism. Total body water in healthy adults accounts for approximately 60% of total human weight.